8.21092

Tetrahydrofurfuryl alcohol polyethylene glycol ether

for synthesis

• 别名: Tetrahydrofurfuryl alcohol polyethylene glycol ether, Glycofurol
• CAS号: 31692-85-0
• MDL號碼: MFCD00801146
• 分類程式碼代碼: 12352104
• NACRES: NA.22

属性

• 品質等級: 200
• 形狀: liquid
• bp: 176 °C/40 hPa
• 密度: 1.08 g/cm³ at 20 °C
• 儲存溫度: 2-30°C
• SMILES 字串: O1C(CCC1)COCCO
• InChI: 1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
• InChI 密鑰: CTPDSKVQLSDPLC-UHFFFAOYSA-N

说明

應用

• Biodegradable microparticle production: A novel green process employing CO2 medium was developed for the production of biodegradable microparticles encapsulating TGF-beta1, utilizing tetrahydrofurfuryl alcohol polyethylene glycol ether, enhancing the sustained release properties of the therapeutic proteins (Swed et al., 2015).


• Nanocarrier devices for targeted drug delivery: Tetrahydrofurfuryl alcohol polyethylene glycol ether was utilized in the formulation of photosensitizer-loaded nanocarrier devices, bridging laboratory and large-scale production, and demonstrating potential in targeted drug delivery systems (Beyer et al., 2015).


• Cardiac tissue-engineering: In cardiac tissue engineering, tetrahydrofurfuryl alcohol polyethylene glycol ether was incorporated into a thermosensitive hydrogel for releasing growth factors from pharmacologically active microcarriers, presenting a biomimetic 3D scaffold that supports cardiac cell growth (Karam et al., 2014).


• Enhanced pharmacokinetics in drug delivery: A self-microemulsifying drug delivery system incorporating tetrahydrofurfuryl alcohol polyethylene glycol ether demonstrated improved pharmacokinetics for tacrolimus, suggesting its efficacy in bioavailability enhancement (von Suesskind-Schwendi et al., 2013).

分析報告

Density (d 20 °C/ 4 °C): 1.080 - 1.090
Identity (IR): passes test

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H319
• 防範說明: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危險分類: Eye Irrit. 2
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 275.0 °F - closed cup
• 閃點（°C）: 135 °C - closed cup