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Key Documents

8.06722

Sigma-Aldrich

Nickel(II) chloride

anhydrous for synthesis

别名:

Nickel(II) chloride, Nickel dichloride

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About This Item

经验公式(希尔记法):
Cl2Ni
CAS号:
分子量:
129.60
分類程式碼代碼:
12352302
酶委員會索引編號:
231-743-0
NACRES:
NA.22

蒸汽壓力

1.33 hPa ( 671 °C)

品質等級

形狀

powder

效力

105 mg/kg LD50, oral (Rat)

pH值

4 (20 °C, 500 g/L in H2O)

mp

1009 °C

密度

3.55 g/cm3

儲存溫度

2-30°C

InChI

1S/2ClH.Ni/h2*1H;/q;;+2/p-2

InChI 密鑰

QMMRZOWCJAIUJA-UHFFFAOYSA-L

應用

Nickel(II) chloride can be used as a catalyst:
  • To synthesize acyclic and cyclic dithioacetals via thioacetalization of aldehydes.
  • To prepare α-aminonitrile derivatives via a one-pot, three-component coupling reaction of aldehydes, amines, and trimethylsilyl cyanide.
  • In the hydrodefluorination of fluoroarenes in the presence of lithium triethylborohydride.

分析報告

Assay (complexometric): 98.0 - 102.0 %
Loss on drying (150 °C; 3h): ≤ 1.0 %

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A Inhalation - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

標靶器官

Lungs

儲存類別代碼

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Nickel (II) chloride as an efficient and useful catalyst for chemoselective thioacetalization of aldehydes
Khan AT, et al.
Tetrahedron Letters, 44(5), 919-922 (2003)
Highly Efficient Nickel (II) Chloride/Bis (tricyclohexylphosphine) nickel (II) Chloride-Cocatalyzed Hydrodefluorination of Fluoroarenes and Trifluorotoluenes with Superhydride
Zhao Wenwen, et al.
Advanced Synthesis & Catalysis, 354(4), 574-578 (2012)

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