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Merck
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Key Documents

16-455

Sigma-Aldrich

Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate

clone 4A4, Upstate®, from mouse

别名:

4A4, anti-phosphoserine, phosphoserine antibody, pan-phosphoserine

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

共軛

peroxidase conjugate

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

4A4, monoclonal

物種活性(以同源性預測)

all

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG1

運輸包裝

wet ice

目標翻譯後修改

phosphorylation (pSer)

一般說明

The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.

特異性

Recognizes proteins containing phosphoserine residues, regardless of origin.

免疫原

Epitope: phosphoserine
Phosphoserine conjugated to KLH.

應用

Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate is an antibody against Phosphoserine for use in WB.
Research Category
Signaling
Research Sub Category
General Post-translation Modification

品質

Routinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.

標靶描述

Varies

外觀

Protein G Purified
100 μL of protein G purified mouse IgG1 in PBS containing 0.05% Kathon® and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.

儲存和穩定性

6 months at 2-8°C from date of shipment.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

法律資訊

Kathon is a registered trademark of Rohm and Haas Co.
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids


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