1.37030

尿素

crystalline, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS

• 别名: 碳酰二胺, 碳酰胺
• 线性分子式: NH₂CONH₂
• CAS号: 57-13-6
• 分子量: 60.06
• Beilstein: 635724
• MDL號碼: MFCD00008022
• 分類程式碼代碼: 12352111
• 酶委員會索引編號: 200-315-5

属性

• 等級: ACS reagent
• 品質等級: 500
• agency: BP; ChP; JP; Ph. Eur.; USP
• 蒸汽壓力: <0.1 hPa ( 20 °C)
• 產品線: EMPROVE^® EXPERT
• 化驗: 98.0-102.0% (HPLC)
• 形狀: crystalline; solid
• 技術: API processing | cocrystal formation: suitable
• pH值: 9 (20 °C, 100 g/L in H₂O)
• mp: 132-135 °C (lit.)
• 密度: 1.335 g/mL at 25 °C (lit.)
• 應用: liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• 儲存溫度: 2-30°C
• SMILES 字串: NC(N)=O
• InChI: 1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
• InChI 密鑰: XSQUKJJJFZCRTK-UHFFFAOYSA-N

说明

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

用于蛋白质变性以及作为不溶性或变性蛋白的温和增溶剂。可用于从已由 6M 盐酸胍变性的样品(如包涵体)复性蛋白质。可与盐酸胍和二硫苏糖醇 (DTT) 一起用于复性变性蛋白以恢复其天然或活性形式。

Urea is typically used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. It is useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. Urea may be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Due to its low microbial and endotoxin limits, Urea cryst. Emprove^® Expert is especially suitable for high-risk applications.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable