1.02330

微晶纤维素

for thin-layer chromatography

• 别名: 微晶纤维素
• 线性分子式: (C₆H₁₀O₅)_n
• CAS号: 9004-34-6
• MDL號碼: MFCD00081512
• 分類程式碼代碼: 41115711
• 酶委員會索引編號: 232-674-9

属性

• 材料: cellulose matrix; plastic support
• 品質等級: 100
• 形狀: microcrystalline
• 自燃溫度: 232 °C
• 效力: >5000 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rabbit)
• 特點: binder Organic Polymer; fluorescent indicator: no
• 包裝: pkg of 500 g
• 技術: thin layer chromatography (TLC): suitable
• 粒徑: 5-40 μm
• 孔徑: 60 Å medium pore diameter
• pH值: 5-7.5 (20 °C, 100 g/L in H₂O, slurry)
• 轉變溫度: flash point 260 °C
• 密度: 1.5 g/cm³ at 20 °C
• 體積密度: 70‑400 kg/m³
• 儲存溫度: 2-30°C
• InChI: 1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1
• InChI 密鑰: GUBGYTABKSRVRQ-WFVLMXAXSA-N

说明

一般說明

标准化的吸附剂确保每一次结果的可靠性。我们广泛的产品谱可满足各种不同的需求。在 TLC 中，硅胶 60 吸附剂被认为是最通用的吸附剂。我们的硅胶 60 产品分若干等级，其颗粒大小介于 5-40 µm 范围内：带石膏粘结剂硅，不带粘结剂硅和带荧光指示剂的硅。我们还提供高品质的氧化铝、微晶纤维素和硅藻石（也称为硅藻土）。

應用

• Study of the influence of cellulose derivatives on physical and analytical attributes of a drug product belonging to BCS class II.: This research explored the impact of cellulose microcrystalline on the physical properties and analytical performance of a class II drug product. The findings demonstrated the role of cellulose microcrystalline in enhancing the stability and dissolution rate of the drug, contributing to improved bioavailability (Domoslawska et al., 2018).
• Application of ethyl cellulose, microcrystalline cellulose and octadecanol for wax based floating solid dispersion pellets.: The study investigated the use of microcrystalline cellulose in the formulation of wax-based floating pellets. The results highlighted its effectiveness in controlling the release profile and enhancing the floating properties of the drug delivery system (Yan et al., 2016).
• Modelling of porosity and waterfronts in cellulosic pellets for understanding drug release behavior.: This paper presented a model for analyzing the porosity and water penetration in cellulosic pellets, providing insights into the drug release mechanisms. The study emphasized the crucial role of microcrystalline cellulose in modulating drug release profiles (Gomez-Carracedo et al., 2010).
• Fast dissolving films made of maltodextrins.: The research explored the incorporation of microcrystalline cellulose in fast-dissolving films, demonstrating its impact on film integrity and dissolution rates. The findings support the use of microcrystalline cellulose in enhancing the performance of oral thin films (Cilurzo et al., 2008).
• Compressibility of floating pellets with verapamil hydrochloride coated with dispersion Kollicoat SR 30 D.: This study evaluated the compressibility and mechanical properties of floating pellets containing microcrystalline cellulose, showing its role in maintaining pellet integrity and controlled drug release (Sawicki & Lunio, 2005).

分析報告

d 10（激光衍射，尺寸分布）：3.0-10.0 µm
d 50（激光衍射，尺寸分布）：10 - 30 µm
d 90（激光衍射，尺寸分布）：30 - 60 µm

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable