推荐产品
生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human, mouse
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
phosphorylation (pSer641/pSer645)
基因資訊
human ... GYS1(2997)
特異性
Glycogen Synthase phosphorylated on serine residues 641 and 645
Predicted to cross-react with rat based on sequence homology (100%), but have not been tested.
免疫原
Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-Glycogen Synthase (Ser641/Ser645).
應用
Anti-phospho-Glycogen Synthase(Ser641/Ser645) Antibody is an antibody against phospho-Glycogen Synthase(Ser641/Ser645) for use in WB.
Research Sub Category
Insulin/Energy Signaling
PI3K, Akt, & mTOR Signaling
Insulin/Energy Signaling
PI3K, Akt, & mTOR Signaling
品質
Routinely evaluated by immunoblot.
標靶描述
85 kDa
外觀
Affinity purified rabbit polyclonal IgG in Dulbecco’s PBS, pH 7.3 with 1.0 mg/mL BSA, 0.05% sodium azide, and 50% glycerol.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Laura Marr et al.
Nature communications, 13(1), 3372-3372 (2022-06-12)
Glycogen is the major glucose reserve in eukaryotes, and defects in glycogen metabolism and structure lead to disease. Glycogenesis involves interaction of glycogenin (GN) with glycogen synthase (GS), where GS is activated by glucose-6-phosphate (G6P) and inactivated by phosphorylation. We
C T Shearn et al.
Biochemistry, 50(19), 3984-3996 (2011-03-29)
The production of reactive aldehydes such as 4-hydroxy-2-nonenal (4-HNE) is a key component of the pathogenesis in a spectrum of hepatic diseases involving oxidative stress such as alcoholic liver disease (ALD). One consequence of ALD is increased insulin resistance in
Cole D Davidson et al.
Journal of the Endocrine Society, 5(8), bvab102-bvab102 (2021-07-15)
Thyroid cancer is the most common endocrine malignancy, and the global incidence has increased rapidly over the past few decades. Anaplastic thyroid cancer (ATC) is highly aggressive, dedifferentiated, and patients have a median survival of fewer than 6 months. Oncogenic
Paras S Minhas et al.
Nature, 590(7844), 122-128 (2021-01-22)
Ageing is characterized by the development of persistent pro-inflammatory responses that contribute to atherosclerosis, metabolic syndrome, cancer and frailty1-3. The ageing brain is also vulnerable to inflammation, as demonstrated by the high prevalence of age-associated cognitive decline and Alzheimer's disease4-6.
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