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Merck
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Key Documents

05-683

Sigma-Aldrich

Anti-Mps1 Antibody, CT, clone 4-112-3

clone 4-112-3, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

4-112-3, monoclonal

物種活性

human

製造商／商標名

Upstate®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

NM_003318

UniProt登錄號

P33981

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... C5AR2(27202)

一般說明

This antibody is known to inhibit the autophos-phorylation/kinase activity of Mps1; Mps1 was previously known as TTK/PYK

特異性

Mps1

免疫原

His-tagged fusion protein corresponding to amino acids 3-856 of human Mps1

應用

Anti-Mps1 Antibody, CT, clone 4-112-3 is a high quality Mouse Monoclonal Antibody for the detection of Mps1 & has been validated in IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

品質

routinely evaluated by immunoblot on HeLa total cell extract

標靶描述

97kDa

外觀

Protein G Chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified

儲存和穩定性

2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

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Volker M Stucke et al.
The EMBO journal, 21(7), 1723-1732 (2002-04-03)
Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p, is a cell cycle-regulated kinase with maximal activity during M
M Kasim Diril et al.
PLoS genetics, 12(9), e1006310-e1006310 (2016-09-16)
The Greatwall kinase/Mastl is an essential gene that indirectly inhibits the phosphatase activity toward mitotic Cdk1 substrates. Here we show that although Mastl knockout (MastlNULL) MEFs enter mitosis, they progress through mitosis without completing cytokinesis despite the presence of misaligned

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