04-973

Anti-CD39 Antibody, clone 5F2

clone 5F2, from mouse

• 别名: ectonucleoside triphosphate diphosphohydrolase 1, ATPDase, ecto-apyrase, NTPDase-1, Ecto-ATP diphosphohydrolase, Lymphoid cell activation antigen, NTPDase 1, Ecto-apyrase, CD39 antigen
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 5F2, monoclonal
• 物種活性: mouse
• 技術: flow cytometry: suitable; western blot: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_033978
• UniProt登錄號: P55772
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Entpd1(12495)

说明

一般說明

Ectonucleoside triphosphate diphosphohydrolase 1 (NTDase 1 or CD39) belongs to the membrane-bound ecto-nucleoside triphosphates diphosphohydrolase family (E-NTPDases) that are characterized for their ability to hydrolyze nucleoside di- and triphosphates, such as ATP, in the presence of cations, i.e. CA2+ and Mg2+. CD39 is an important membrane protein containing two transmembrane domains and a large NTPDase active, extracellular region containing apyrase conserved regions. It is heavily glycosolated, having six known N-glycosolation sites, and functions on the plasma membrane’s outer surface. CD39 initiates the metabolism, of ATP and ADP to adenosine through a 2-step exzymatic reaction, providing extracellular adenosine for the purpose of regulating various inflammatory endpoints. It is a putative marker for B-cell activation and its expression has also been observed on NK-cells, dendritic cells, T-cells, and vascular endothelial cells. CD39 is a known inhibitor of ADP-induced platelet aggregation and may also play a role in angiogenesis.

特異性

This antibody recognizes CD39.

免疫原

Recombinant protein corresponding to mouse CD39.

應用

This Anti-CD39 Antibody, clone 5F2 is validated for use in FC, WB for the detection of CD39.

Western Blot Analysis: A previous lot was used by an independent laboratory in WB.

品質

Evaluated by Flow Cytometry in BALB/c splenocytes.

Flow Cytometry Analysis: 0.1 µg/mL of this antibody detected CD39 in BALB/c splenocytes.

標靶描述

~ 100 kDa
It has been published that CD39 shows molecular weights between ~70-100 kDa (Wang, T.F. et al., 1996).

外觀

Format: Purified

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable