推荐产品
等級
certified reference material
品質等級
形狀
liquid
特點
Snap-N-Spike®/Snap-N-Shoot®
包裝
ampule of 1 mL
製造商／商標名
Cerilliant®
濃度
100 μg/mL in methanol
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
forensics and toxicology
形式
single component solution
儲存溫度
−20°C
SMILES 字串
OC1=C(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C([2H])=C([2H])C([2H])=C1C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
InChI
1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3/i1D3,2D3,3D3,4D3,5D,6D,7D,8D,9D
InChI 密鑰
OLBCVFGFOZPWHH-ACWNEFEHSA-N
一般說明
丙泊酚，也称Diprivan®，是一种短效催眠药物，通过静脉注射给药用于诱导和维持全身麻醉和镇静作用。该内标物适用于多种用途，包括法医和法医毒理学分析、同位素稀释方法、校准品制备以及血浆或全血的药物监测。
應用
- 法医分析中的异丙酚-D₁₇：研究人员利用异丙酚-D来进行腐烂尸体的药物检测，以此来证实连环凶杀案中的陈词证据（testimonial evidence），该研究证明了其在复杂法医场景中的价值(Ottaviano et al., 2021）。
- 异丙酚-D₁₇的药代动力学研究：在一项健康中国受试者中进行的生物等效性研究中，研究人员使用丙泊酚-D开发了一种灵敏的LC-APIC-MS/MS方法来定量测定丙泊酚，该研究加深了我们对其药代动力学的理解（Tang et al., 2020）。
- 使用丙泊酚-D₁₇进行的分析方法评估：丙泊酚检测用LC-MS/MS和GC-MS法的比较分析彰显了丙泊酚-D₁₇改进法医学和临床毒理学分析方法的作用（Vaiano et al., 2015）。
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Diprivan is a registered trademark of Abraxis Bioscience, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
49.5 °F - closed cup
閃點（°C）
9.7 °C - closed cup
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