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Merck
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文件

T5411

Supelco

睾酮 溶液

1.0 mg/mL in 1,2-dimethoxyethane, drug standard

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About This Item

CAS号:
58-22-0
Beilstein:
1915399
MDL號碼:
MFCD00003654
分類程式碼代碼:
41116107
PubChem物質ID:
329826822
NACRES:
NA.24

等級

drug standard

品質等級

200

drug control

Home Office Schedule 4.2

濃度

1.0 mg/mL in 1,2-dimethoxyethane

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

clinical testing

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H]

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChI 密鑰

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

基因資訊

human ... AR(367) , EBP(10682) , ESR1(2099) , PGR(5241) , SERPINA6(866) , SHBG(6462)
mouse ... Esr1(13982)
rat ... Ar(24208) , Esr1(24890) , Nr3c1(24413) , Nr3c2(25672) , Pgr(25154)

相关类别

應用

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訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

安全危害

EUH019

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

41.0 °F - closed cup

閃點（°C）

5 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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分析证书(COA)

Lot/Batch Number
SLCJ3266
SLCF8996
SLCC9052
SLBV0266
SLBN9226V

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Julia K Slezak et al.
Scientific reports, 7(1), 17636-17636 (2017-12-17)
The concentrations of testosterone deposited in hair during hair growth may provide a retrospective reflection of the concentrations of bioactive testosterone in plasma. The objective of this study was to develop a radioimmunoassay with a sufficiently low limit of detection
Line Cantin et al.
The Journal of biological chemistry, 282(42), 30910-30919 (2007-08-23)
Antiandrogens are commonly used to treat androgen-dependent disorders. The currently used drugs unfortunately possess very weak affinity for the human AR (hAR), thus indicating the need to develop new high-affinity steroidal antiandrogens. Our compounds are specially designed to impede repositioning
Arjan van Oeveren et al.
Journal of medicinal chemistry, 49(21), 6143-6146 (2006-10-13)
The androgen receptor is a member of the extended family of nuclear receptors and is widely distributed throughout the body. Androgen therapy is used to compensate for low levels of the natural hormones testosterone (T) and dihydrotestosterone and consists of
Annu A Söderholm et al.
Journal of medicinal chemistry, 48(4), 917-925 (2005-02-18)
We studied the three-dimensional quantitative structure-activity relationships (3D QSAR) of 70 structurally and functionally diverse androgen receptor (AR) binding compounds using the comparative molecular similarity indices analysis (CoMSIA) method. The compound set contained 67 nonsteroidal analogues of flutamide, nilutamide, and
Jenny Roy et al.
Bioorganic & medicinal chemistry, 15(8), 3003-3018 (2007-03-06)
In our efforts to develop compounds with therapeutic potential as antiandrogens, we synthesized a series of 5alpha-androstane-3alpha,17beta-diol derivatives with a fixed side-chain length of 3-methylenes at C-16alpha, but bearing a diversity of functional groups at the end. Among these, the
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