N-911

去甲安定-d₅ 溶液

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 经验公式（希尔记法）: C₁₅D₅H₆ClN₂O
• CAS号: 65891-80-7
• 分子量: 275.74
• EC號碼: 200-659-6
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material
• 形狀: liquid
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• 濃度: 1 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: [2H]c1c([2H])c([2H])c(c([2H])c1[2H])C2=NCC(=O)Nc3ccc(Cl)cc23
• InChI: 1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)/i1D,2D,3D,4D,5D
• InChI 密鑰: AKPLHCDWDRPJGD-RALIUCGRSA-N

说明

一般說明

去甲西泮是一种苯二氮卓类药物，用于治疗焦虑和惊恐发作。该稳定标记的内标适用于通过LC/MS或GC/MS定量尿液、血清或血浆中的去甲西泮水平，用于尿液药物检验、临床毒理学、法医分析或同位素稀释方法。去甲西泮也是苯二氮卓类药物地西泮和氯氮卓的主要尿液代谢产物。

應用

• Development of UPLC-MS/MS Screening for Psychoactive Drugs: Nordiazepam-d5 was utilized in the development and validation of a rapid ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. This method effectively detects 68 psychoactive drugs and metabolites in whole blood, demonstrating its application in forensic toxicology and post-mortem analysis, enhancing drug metabolism studies and analytical testing capabilities (Barone et al., 2023).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup