推荐产品
等級
certified reference material
形狀
liquid
特點
Snap-N-Spike®/Snap-N-Shoot®
包裝
ampule of 1 mL
製造商／商標名
Cerilliant®
濃度
1.0 mg/mL in acetonitrile
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
clinical testing
pharmaceutical (small molecule)
格式
single component solution
儲存溫度
−20°C
SMILES 字串
CC(C(O)=O)C(O)=O
InChI
1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)
InChI 密鑰
ZIYVHBGGAOATLY-UHFFFAOYSA-N
一般說明
甲基丙二酸是维生素B12 缺乏症和甲基丙二酸血症的指标。该经认证的加标溶液®适用于使用GC/MS或LC/MS制备临床和诊断测试中的校准品或质控品。
應用
- Organic acid analysis for metabolic profiling: Research highlighted the integration of soil microbiota and metabolome, where methylmalonic acid was part of the metabolic profiling, revealing insights into how controlled release fertilizer impacts sugarcane growth, emphasizing the compound′s role in agricultural biotechnology (Yuan et al., 2023).
- Vitamin B12 deficiency research: Methylmalonic acid was featured in research on the cellular mechanisms affecting the MAFB/NOTCH3 axis in osteosarcoma, where its levels could potentially reflect perturbations relevant to vitamin B12 deficiency, aiding in better understanding of disease progression (Zhang et al., 2024).
- Methylmalonic acid standard for mass spectrometry analysis: The analysis of soybean root systems under varying nutrient conditions included methylmalonic acid as a standard in mass spectrometry to better understand nutrient uptake mechanisms, showcasing its utility in plant physiology and biochemistry studies (Qin et al., 2023).
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
35.6 °F - closed cup
閃點（°C）
2 °C - closed cup
其他客户在看
Serum cobalamin and methylmalonic acid concentrations in dogs with chronic gastrointestinal disease.
Nora Berghoff et al.
American journal of veterinary research, 74(1), 84-89 (2012-12-29)
To determine the prevalence of hypocobalaminemia or methylmalonic acidemia (or both) in dogs with chronic gastrointestinal disease. Serum samples from 56 dogs with chronic gastrointestinal disease and 43 control dogs. Serum cobalamin and methylmalonic acid (MMA) concentrations were measured in
Acute renal failure potentiates methylmalonate-induced oxidative stress in brain and kidney of rats.
P F Schuck et al.
Free radical research, 47(3), 233-240 (2013-01-10)
Tissue methylmalonic acid (MMA) accumulation is the biochemical hallmark of methylmalonic acidemia. The disease is clinically characterized by progressive neurological deterioration and kidney failure, whose pathophysiology is still unclear. In the present work we investigated the effects of acute MMA
Setareh Shahab-Ferdows et al.
The Journal of nutrition, 142(10), 1881-1887 (2012-08-24)
A high prevalence of low serum vitamin B-12 concentrations has been reported in studies and surveys in Latin America including Mexico, but the functional consequences are unknown. This randomized controlled trial assessed the response to a high-dose vitamin B-12 supplementation
Carla Dullemeijer et al.
The American journal of clinical nutrition, 97(2), 390-402 (2012-12-28)
Many randomized controlled trials (RCTs) and observational studies have provided information on the association between vitamin B-12 intake and biomarkers. The use of these data to estimate dose-response relations provides a useful means to summarize the body of evidence. We
Takayuki Watanabe et al.
Journal of feline medicine and surgery, 14(12), 942-945 (2012-08-22)
A 10-year-old domestic shorthair cat showed anorexia, lethargy and ptyalism with hyperammonaemia. Portosystemic shunts were not identified by computed tomography angiography. Biopsy results revealed mild interstinal nephritis and no lesion in the liver. Analysis of urine revealed the presence of
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