B-052

(±)-Bupropion-D₉ hydrochloride solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 经验公式（希尔记法）: C₁₃H₉D₉ClNO · HCl
• CAS号: 1189725-26-5
• 分子量: 285.26
• EC號碼: 200-659-6
• MDL號碼: MFCD08063410
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329773116
• NACRES: NA.24

属性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: (Snap-N-Spike^®)
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 形式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: CC(NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C(C1=CC=CC(Cl)=C1)=O.Cl
• InChI: 1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H/i2D3,3D3,4D3;
• InChI 密鑰: HEYVINCGKDONRU-WWMMTMLWSA-N

说明

一般說明

Bupropion is an antidepressant and smoking cessation drug sold under the trade names Wellbutrin^® and Zyban^®. Suitable uses for this certified solution standard include as an internal standard for quantitation of bupropion levels in biological matrices such as urine or isotope dilution methods by LC/MS or GC/MS for clinical toxicology, urine drug testing, or forensic analysis applications.

應用

• Pharmaceutical and nanotechnology applications: Bupropion-D9 hydrochloride is used in the development of UV-triggered drug release systems involving mesoporous titanium nanoparticles loaded with pharmaceutical agents, demonstrating its utility in enhancing drug delivery mechanisms and controlled release technologies (Zuo et al., 2024).
• Dermatological research: The solution is integral in evaluating antioxidant activities and the treatment of conditions such as eczema using berberine hydrochloride-loaded liposomes, highlighting its role in dermatological research and therapeutic applications (Shen et al., 2024).
• Cancer therapy: Utilized in the synthesis of small-molecule EGFR inhibitors for cancer therapy, Bupropion-D9 HCl serves as a stable isotope-labeled compound, crucial for understanding the pharmacokinetics and biochemical interactions of potential cancer treatments (Wang et al., 2024).
• Biomedical polymer research: The compound supports studies on the effects of various factors on poly(lactic-co-glycolic acid) nanoparticle properties, contributing to advancements in biodegradable polymer research for drug encapsulation and release behaviors (Wang et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Wellbutrin is a registered trademark of GlaxoSmithKline LLC

Zyban is a registered trademark of Everris International B.V.

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F
• 閃點（°C）: 9.7 °C