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形狀
methanol solution
包裝
pkg of 1 × 1 mL (LM1701-1EA)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
~10 μg/mL (Refer to C of A for lot specific concentration. )
應用
lipidomics
metabolomics
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]
InChI
1S/C20H39O7P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(22)26-17-19(21)18-27-28(23,24)25;/h7-8,19,21H,2-6,9-18H2,1H3,(H2,23,24,25);1H3/b8-7-;/t19-;/m1./s1
一般說明
Lysophosphatidic acid (Lyso PA) is a water-soluble lipid, localized to all cells and tissues in mammals.
應用
17:1 Lyso PA or 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt) has been used as an internal standard for unsaturated lysophosphatidic acid (LPA) ester and cyclic LPA ethers in reversed-phase ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS).
生化／生理作用
Lysophosphatidic acid (Lyso PA) is considered as a biological modulator of various functions in the cell. It is a potent signaling molecule with growth-factor-like actions. Lyso PA regulates cell proliferation, survival, cytoskeletal modification and calcium influx. It is associated with smooth-muscle contraction and platelet aggregation. It is also known to regulate blood pressure. Lyso PA possess extensive biological actions and is involved in the progression of several human cancer.
包裝
2 mL Amber Glass Sealed Ampule (LM1701-1EA)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
49.5 °F - closed cup
閃點（°C）
9.7 °C - closed cup
其他客户在看
Gordon B Mills et al.
Nature reviews. Cancer, 3(8), 582-591 (2003-08-02)
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation, migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA production, receptor expression and signalling probably contribute to cancer initiation, progression and metastasis. The recent identification of ecto-enzymes that
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