推荐产品
形狀
powder
包裝
pkg of 1 × 25 mg (890808P-25mg)
pkg of 1 × 5 mg (890808P-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand
應用
vaccine development
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
O[C@H]([C@@H](COC(CCCCCCCCCCCCCCCCCCCCC)=O)O[C@H](O[C@@H](O[C@@H]([C@H]([C@@H]1O)O)COC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@@H]1O)[C@@H]2O)[C@@H]2O
一般說明
22:0 Trehalose is a bioactive glycolipid and an analog of mycobacterial cord factor.
應用
22:0 Trehalose has been used as an adjuvant for Chlamydia vaccine. It has also been used as a component in adjuvant DMT (dimethyldioctadecylammonium/monophosphoryl lipid A/trehalose 6,6′-dibehenate (DDA/MPL/TDB)) to prepare DMT liposome adjuvanted CTT3H (polyprotein) vaccine.
生化/生理作用
Incorporation of trehalose 6,6′-dibehenate (TDB) into cationic liposomes composed of the quaternary ammonium compound dimethyldioctadecylammonium (DDA) produce an adjuvant system which induces a powerful cell-mediated immune response and a strong antibody response, desirable for a high number of disease targets. It acts as an immunomodulator. 22:0 Trehalose is considered less toxic and an efficient vaccine adjuvant for tuberculosis.
包裝
5 mL Amber Glass Screw Cap Vial (890808P-25mg)
5 mL Amber Glass Screw Cap Vial (890808P-5mg)
其他說明
For R&D use only. Not for drug, household, or other uses.
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Human vaccines & immunotherapeutics, 11(6), 1456-1464 (2015-04-24)
Different strategies have been proposed for the development of protein subunit vaccine candidates for tuberculosis (TB), which shows better safety than other types of candidates and the currently used Bacillus Calmette-Guérin (BCG) vaccine. In order to develop more effective protein
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