推荐产品
形狀
powder
包裝
package of 1 × 1 mg (890000P-1mg)
package of 1 × 5 mg (890000P-5MG)
製造商／商標名
Avanti Research™ - A Croda Brand 890000P
應用
advanced drug delivery
脂質類型
transfection
cationic lipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
CCCCCCCC/C=C\CCCCCCCCOC1=C(OCCCCCCCC/C=C\CCCCCCCC)C=C(C(NCCNC(C([NH2+]CCC[NH3+])CCC[N+](CCC[NH3+])([H])CCC[NH3+])=O)=O)C=C1.[5Cl-]
應用
MVL5已用于脂质体制备。
生化／生理作用
MVL5是阳离子脂质，是五价分子。它与脂质体制剂中的1，2-二油酰基-sn-甘油-3-乙基磷酸胆碱（DOPC）结合使用，以实现有效的基因转染。认为其毒性较小。
包裝
5 mL棕色玻璃螺旋盖小瓶（890000P-1MG）
5 mL棕色玻璃螺旋盖小瓶（890000P-5MG）
5 mL棕色玻璃螺旋盖小瓶（890000P-5MG）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
No data available
閃點（°C）
No data available
Chia-Ling Chan et al.
The journal of gene medicine, 16(3-4), 84-96 (2014-04-23)
Cationic liposome (CL)-DNA complexes are promising gene delivery vectors with potential application in gene therapy. A key challenge in creating CL-DNA complexes for application is that their transfection efficiency (TE) is adversely affected by serum. In particular, little is known
Polyamine Drug Discovery, 226-226 (2012)
Kai Ewert et al.
Journal of medicinal chemistry, 45(23), 5023-5029 (2002-11-01)
Lipid-mediated delivery of DNA into cells holds great promise both for gene therapy and basic research applications. This paper describes the efficient and facile synthesis and the characterization of a new multivalent cationic lipid with a double-branched headgroup structure for
Asymmetric cationic liposomes designed for heat-activated association with cells
Jing Y, et al.
Colloids and Surfaces. B, Biointerfaces, 151, 112-118 (2017)
Endosomal escape and transfection efficiency of PEGylated cationic liposome-DNA complexes prepared with an acid-labile PEG-lipid
Chan CL, et al.
Biomaterials, 33(19), 4928-4935 (2012)
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