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Merck

870432P

Avanti

C18:1 anandamide

Avanti Research - A Croda Brand 870432P, powder

别名:

9Z-octadecenoylethanolamide

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About This Item

经验公式(希尔记法):
C20H39NO2
CAS号:
分子量:
325.53
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 5 mg (870432P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 870432P

脂質類型

bioactive lipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

O=C(CCCCCCC/C=C\CCCCCCCC)NCCO

InChI

1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-

InChI 密鑰

BOWVQLFMWHZBEF-KTKRTIGZSA-N

一般說明

Anandamide is an endocannabinoid. It acts as a ligand for cannabinoid (CB) receptors CB1 and CB2 in the brain and peripheral tissues. It is synthesized from glycerophospho-N-arachidonoylethanolamine (GP-NArE) precursor by the reaction catalyzed by glycerophosphodiesterase 1.

生化/生理作用

Anandamide plays a vital role in various processes including inflammation, pain, and appetite.

包裝

5 mL Clear Glass Sealed Ampule (870432P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mohammad Younus et al.
Langmuir : the ACS journal of surfaces and colloids, 32(35), 8942-8950 (2016-08-16)
Oleoylethanolamide (OEA) is an endogenous lipid with neuroprotective properties and the fortification of its concentration in the brain can be beneficial in the treatment of many neurodegenerative disorders. However, OEA is rapidly eliminated by hydrolysis in vivo, limiting its therapeutic
Mohammed K Hankir et al.
Frontiers in neuroscience, 10, 620-620 (2017-01-31)
Brain μ-opioid receptors (MORs) stimulate high-fat (HF) feeding and have been implicated in the distinct long term outcomes on body weight of bariatric surgery and dieting. Whether alterations in fat appetite specifically following these disparate weight loss interventions relate to
Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain
Astarita G, et al.
Journal of Lipid Research, 49(1), 48-57 (2008)
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
Long J, et al.
Nature Chemical Biology, 5(1), 37-37 (2009)
Gabriel M Simon et al.
The Journal of biological chemistry, 283(14), 9341-9349 (2008-01-30)
Anandamide (AEA) is an endogenous ligand of cannabinoid receptors and a well characterized mediator of many physiological processes including inflammation, pain, and appetite. The biosynthetic pathway(s) for anandamide and its N-acyl ethanolamine (NAE) congeners remain enigmatic. Previously, we proposed an

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