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Merck

860692P

Avanti

C16:0 Ceramide (d18:2(4E,8Z)/16:0)

Avanti Polar Lipids 860692P, powder

别名:

N-palmitoyl-D-erythro-sphingosine (d18:2(4E,8Z) base)

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About This Item

经验公式(希尔记法):
C34H65NO3
分子量:
535.88
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 1 mg (860692P-1mg)

製造商/商標名

Avanti Polar Lipids 860692P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@@](NC(CCCCCCCCCCCCCCC)=O)([H])[C@]([H])(O)/C=C/CC/C=C\CCCCCCCCC

一般說明

C16:0 Ceramide (d18:2(4E,8Z)/16:0) or N-palmitoyl-D-erythro-sphingosine (d18:2(4E,8Z) base) is a long chain ceramide derived from sphingosine containing two double bonds with palmitic acid. C16:0 Ceramide synthesis is catalyzed by the enzyme ceramide synthase 6 (CerS6).

生化/生理作用

C16:0-ceramide facilitates obesity-related insulin resistance. It exhibits pro-apoptotic function. Elevated levels of C16:0-ceramide has been observed in adipose tissue of obese patients.

包裝

5 mL Amber Glass Screw Cap Vial (860692P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

No data available

閃點(°C)

No data available


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Sarah M Turpin et al.
Cell metabolism, 20(4), 678-686 (2014-10-09)
Ceramides increase during obesity and promote insulin resistance. Ceramides vary in acyl-chain lengths from C14:0 to C30:0 and are synthesized by six ceramide synthase enzymes (CerS1-6). It remains unresolved whether obesity-associated alterations of specific CerSs and their defined acyl-chain length

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