810603C

16:0-10 Doxyl PC

Avanti Research^™ - A Croda Brand 810603C

• 别名: 1-palmitoyl-2-stearoyl-(10-doxyl)-sn-glycero-3-phosphocholine
• 经验公式（希尔记法）: C₄₆H₉₀N₂O₁₀P
• CAS号: 188004-25-3
• 分子量: 862.19
• 分類程式碼代碼: 41141825
• NACRES: NA.12

属性

• 化驗: >99% (TLC)
• 形狀: liquid
• 包裝: pkg of 1 × 1 mL (810603C-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 810603C
• 濃度: 1 mg/mL (810603C-1mg)
• 脂質類型: ESR probes; phospholipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine metabolism.

應用

16:0-10 Doxyl PC may be used in vesicles for quenching PT-(1–46)F4W fluorescence. It may also be used in vesicles to check the fluorescence emission spectra in order to measure the penetration depth of the peptides′ tryptophan residues in lipid bilayer.

生化／生理作用

Phosphatidylcholine (PC) lowers the levels of cholesterol and triglycerides.

包裝

5 mL Clear Glass Sealed Ampule (810603C-1mg)

準備報告

Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 防範說明: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危險分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 標靶器官: Central nervous system, Liver,Kidney
• 水污染物質分類（WGK）: WGK 3