810262P

C11 TopFluor^™ Ceramide

N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosine, powder

• 别名: N-[11-(TopFluor)undecanoyl]-D-erythro-sphingosine
• 经验公式（希尔记法）: C₄₂H₇₀N₃O₃F₂
• CAS号: 1246355-58-7
• 分子量: 703.02
• MDL號碼: MFCD22416770
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 250 μg (810262P-250ug)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 810262P
• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

Ceramide, a bioactive sphingolipid belongs to the sphingolipid family of cell lipids. This pore-forming member is insoluble in water. It is a hygroscopic and light sensitive lipid.

應用

C11 TopFluor^™ Ceramide may be used:

• in the ceramide and B-cell lymphoma-extra-large (Bcl-xL) binding studies to study the effect on ceramide channel formation
• as a tracer in confocal microscopy to treat T84 cells in order to study its localization in sphingomyelinase (SMase)-induced F-actin structures
• to study its effect on the migration of pancreatic cancer stem cells (PCSC) using confocal microscopy

生化／生理作用

Ceramide is known to participate in apoptosis, mediated by mitochondria. Ceramide channels plays a key role in the onset of apoptosis in vivo.

包裝

5 mL Amber Glass Screw Cap Vial (810262P-250ug)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

TopFluor is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids