791275P

18:0 PE-DTPA (Gd)

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt), powder

• 别名: 1,2-dioctadecanoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt); DSPE-DTPA (Gd)
• 经验公式（希尔记法）: C₅₅H₁₀₆GdN₆O₁₇P
• CAS号: 2260795-19-3
• 分子量: 1311.68
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 5 mg (791275P-5mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 791275P
• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt) (18:0 PE-DTPA (Gd)) are sparing soluble in alcohol and well soluble in a solvent mixture consisting of chloroform and methanol in the ratio of 4:1, v/v. 18:0 PE-DTPA (Gd) is a synthetic phospholipid derivative ethanolamine. The DTPA is attached to gadolinium ion.

應用

18:0 PE-DTPA (Gd) has been used:

• as a component of Gadolinium-liposome preparation
• in the nanodics preparation for nuclear magnetic resonance (NMR) studies
• in construction of cysteine-arginine-glutamic acid-lysine alanine (CREKA) based peptide amphiphile micelles (PAMs) for the magnetic resonance imaging (MRI) studies
• as a spin-labeled lipid for supported lipid bilayer incorporation for cryo transmission electron microscopy studies

生化／生理作用

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt) (18:0 PE-DTPA (Gd)) phospholipid based liposomes are useful in magnetic resonance imaging (MRI) and multimodal imaging. Apart from being a MRI contrast agent, PE-DTPA (Gd) liposome is also flexible for modification for binding different targets using copper–free click–chemistry methodology.

包裝

5 mL Amber Glass Screw Cap Vial (791275P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3