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化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 2.5 mL (780200C-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand 780200C
濃度
10 mg/mL (780200C-25mg)
應用
advanced drug delivery
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
1，2-二棕榈酰基-sn-甘油-3-磷酸乙醇胺-N-[4-（对马来酰亚胺基甲基）环己烷-羧酰胺]（16:0 PE MCC）是一种脂质，其脂质包含通过其磷酸基团与两个棕榈酸连接的磷酸乙醇胺并通过其氨基形成马来酰亚胺部分。马来酰亚胺基团是硫醇受体，而16:0 PE MCC是基于马来酰亚胺的脂化试剂。
應用
16:0 PE MCC（1，2-二棕榈酰-sn-甘油-3-磷酸乙醇胺-N-4-（对马来酰亚胺基甲基）环己烷-羧酰胺）可用于：
- 制备与人免疫缺陷病毒（HIV-1）包膜糖蛋白三聚体结合的脂质体
- 制备寡核苷酸修饰囊泡
- 扁平硅片的功能化
- 脂质囊泡制备
生化／生理作用
功能化脂质体中的1，2-二棕榈酰基-sn-甘油-3-磷酸乙醇胺-N-[4-（对马来酰亚胺基甲基）环己烷-羧酰胺]（1，2-双（二苯基膦基）乙烷(DPPE)-MCC）有助于共价连接通过马来酰亚胺基团。它在肽转运研究中充当载体。
包裝
5 mL透明玻璃密封安瓿（780200C-25mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system
水污染物質分類（WGK）
WGK 3
Malin Edvardsson et al.
Analytical chemistry, 81(1), 349-361 (2008-11-28)
A novel setup was recently developed, combining quartz crystal microbalance with dissipation monitoring (QCM-D) and optical reflectometry for measurements on one and the same surface of, for example, biomolecular adlayers and interactions ( Rev. Sci. Instr. 2008 , 79 075107
Xiaoming Zhang et al.
Biochemical and biophysical research communications, 349(3), 920-924 (2006-09-15)
Human serum albumin (HSA) patterns have been successfully fabricated for the deposition of lipid bilayer, 1,2-dimyristoyl-sglycerophosphate (DMPA), by making use of the micro-contact printing (microCP) technique and liposome fusion. Confocal laser scanning microscopy (CLSM) results indicate that lipid bilayer has
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
Sebastian Ols et al.
Cell reports, 30(12), 3964-3971 (2020-03-27)
Although intramuscular (i.m.) administration is the most commonly used route for licensed vaccines, subcutaneous (s.c.) delivery is being explored for several new vaccines under development. Here, we use rhesus macaques, physiologically relevant to humans, to identify the anatomical compartments and
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