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一般說明
用于吸附、分配和离子交换技术的薄层色谱 (TLC) 板。可选择玻璃、聚酯或铝质等六种不同材料的板。Sigma-Aldrich 薄层层析板上的硅胶吸附层含有聚合物粘合剂；高度纯化的硅胶板含有石膏/聚合物粘合剂。
- 硅胶 — 用于从弱极性到强极性的分离，孔径 60Å
- 高纯度硅胶 —·经酸洗，用于分离黄曲霉素
- 纤维素 —·用于分配色谱（SigmaCell 100 型纤维素）
- 纤维素 PEI —·用于分离弱阴离子（氨基酸、多肽）。PEI 板可能会稍稍变黄，这会影响分离。使用蒸馏水对板进行预展开，尽可能去除黄色。
- 手性硅 —·用于以配体交换方式分离光学活性同分异构体，孔径 60Å
應用
Sigma-Aldrich TLC板在GTPase活性检测和脂质提取/分析中可用于TLC分析。
法律資訊
SIGMA-ALDRICH is a registered trademark of Merck KGaA, Darmstadt, Germany
Heiko Runz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(5), 1679-1689 (2002-03-07)
Generation of amyloid-beta (Abeta) from the amyloid precursor protein (APP) requires proteolytic cleavage by two proteases, beta- and gamma-secretase. Several lines of evidence suggest a role for cholesterol on secretase activities, although the responsible cellular mechanisms remain unclear. Here we
Chuang-Rung Chang et al.
The Journal of biological chemistry, 282(30), 21583-21587 (2007-06-08)
Mitochondria in cells comprise a tubulovesicular reticulum shaped by dynamic fission and fusion events. The multimeric dynamin-like GTPase Drp1 is a critical protein mediating mitochondrial division. It harbors multiple motifs including GTP-binding, middle, and GTPase effector (GED) domains that are
Sofi Eriksson et al.
Nature communications, 6, 6479-6479 (2015-03-21)
Across phyla, reduced nicotinamide adenine dinucleotide phosphate (NADPH) transfers intracellular reducing power to thioredoxin reductase-1 (TrxR1) and glutathione reductase (GR), thereby supporting fundamental housekeeping and antioxidant pathways. Here we show that a third, NADPH-independent pathway can bypass the need for
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