857270

(+)-辛可宁

85%

• 别名: 辛可宁 单盐酸盐 二水合物
• 经验公式（希尔记法）: C₁₉H₂₂N₂O
• CAS号: 118-10-5
• 分子量: 294.39
• Beilstein: 89689
• EC號碼: 204-234-6
• MDL號碼: MFCD00064372
• 分類程式碼代碼: 12352104
• PubChem物質ID: 24888435
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: 85%
• 形狀: solid
• 光學活性: [α]23/D +228°, c = 0.5 in ethanol
• mp: 258-260 °C (lit.)
• 官能基: hydroxyl
• SMILES 字串: [H][C@@]12CCN(C[C@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccccc34
• InChI: 1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18+,19-/m0/s1
• InChI 密鑰: KMPWYEUPVWOPIM-QAMTZSDWSA-N

说明

一般說明

(+)-Cinchonine, one of the alkaloids found in the barks of cinchona tree, is mainly used in the treatment of malaria. It belongs to the monoclinic crystal system and P2₁ space group. The solubility of cinchonine can be improved by the formation of inclusion complexes with cyclodextrins.

應用

(+)-Cinchonine, in the presence of lithium diisopropylamide (LDA) forms a complex, which can catalyze the asymmetric conjugate addition of benzyl- and alkylphosphonates to aromatic and heteroaromatic nitroalkenes to form the corresponding adducts.

其他說明

残留二氢金鸡宁

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H317
• 防範說明: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• 危險分類: Acute Tox. 4 Oral - Skin Sens. 1A
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves