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形狀
solid
品質等級
光學活性
[α]/D 0°, c = 0.5% in chloroform
分子量
average Mn 10,000
降解時間
<6 months
mp
287-293 °C
蛋白質二硫鍵異構酶
≤1.2
儲存溫度
2-8°C
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應用
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.
The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).
Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.
Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.
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