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Merck
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文件

765112

Sigma-Aldrich

聚 L -丙交酯

average Mn 10,000, PDI ≤1.1

别名:

PLA, PLLA, 聚乳酸, L-乳酸聚合物, PLA，聚（L-L-乳酸）

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About This Item

线性分子式:
H(C3H4O2)nOCH3
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid

光學活性

[α]22/D -150°, c = 0.5% in chloroform

分子量

average Mn 10,000

降解時間

>3 years

轉變溫度

Tm 162-167 °C

蛋白質二硫鍵異構酶

≤1.1

儲存溫度

2-8°C

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相关类别

一般說明

聚(L-乳酸)一种具有强旋光性和良好力学性能的半晶聚合物。它主要用于合成可降解聚合物，用于矫形装置、牙科应用，作为自体移植的新皮肤、伤口覆盖物、吻合系统和支架的支架。它们是可生物降解的，因为聚酯骨架通过简单水解降解，形成无毒化合物。

應用

药物释放包括包被纳米颗粒；端基官能化；大分子引发剂或嵌段前体。

特點和優勢

高初始强度，良好的强度保持性和高结晶度，高达 70％，这反过来又导致了非常缓慢的降解速率。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Effect of poly (ethylene glycol)-block- poly (L-lactide) on the poly [(R)-3-hydroxybutyrate]/poly (L-lactide) blends
Yoon, J. S., Lee, W. S., Kim, K. S., Chin, I. J., Kim, M. N., & Kim, C.
Eur. Polymer J., 36(2), 435-442 (2000)
Chemical synthesis of polylactide and its copolymers for medical applications
Bendix, D.
Polymer Degradation and Stability, 59(1), 129-135 (1998)
Synthesis and thermal properties of novel star-shaped poly (l-lactide)s with starburst PAMAM-OH dendrimer macroinitiator.
Zhao, Y. L., Cai, Q., Jiang, J., Shuai, X. T., Bei, J. Z., Chen, C. F., & Xi, F.
Polymer, 43(22), 5819-5825 (2002)
Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
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