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Merck

679097

Sigma-Aldrich

(R)-(-)-2-甲基吡咯烷

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About This Item

经验公式(希尔记法):
C5H11N
CAS号:
分子量:
85.15
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

折射率

n20/D 1.4353

密度

0.842 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

C[C@@H]1CCCN1

InChI

1S/C5H11N/c1-5-3-2-4-6-5/h5-6H,2-4H2,1H3/t5-/m1/s1

InChI 密鑰

RGHPCLZJAFCTIK-RXMQYKEDSA-N

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應用

(R)-(−)-2-Methylpyrrolidine, an optically active amine that can be used as a key building block to synthesize:
  • 4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
  • Naphthalenoid histamine H3 receptor antagonist.
  • Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2.

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

45.0 °F - closed cup

閃點(°C)

7.22 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析证书(COA)

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Synthesis and structure?activity relationships of 4, 5-fused pyridazinones as histamine H 3 receptor antagonists
Tao, Ming, et al.
Bioorganic & Medicinal Chemistry Letters, 21.20, 6126-6130 (2011)
Identification of pyridazin-3-one derivatives as potent, selective histamine H 3 receptor inverse agonists with robust wake activity
Hudkins, Robert L., et al.
Bioorganic & Medicinal Chemistry Letters, 21.18, 5493-5497 (2011)
Synthesis and evaluation of pyridazinone?phenethylamine derivatives as selective and orally bioavailable histamine H 3 receptor antagonists with robust wake-promoting activity
reddy Dandu, Reddeppa, et al.
Bioorganic & Medicinal Chemistry Letters, 21.21, 6362-6365 (2011)
Organic Process Research & Development, 11, 1004-1004 (2007)
A new class of potent non-imidazole H 3 antagonists: 2-aminoethylbenzofurans
Cowart, Marlon, et al.
Bioorganic & Medicinal Chemistry Letters, 14.3, 689-693 (2004)

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