545872

(R)-(+)-氨鲁米特

97%

• 经验公式（希尔记法）: C₁₃H₁₆N₂O₂
• CAS号: 55511-44-9
• 分子量: 232.28
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24878857
• NACRES: NA.22

属性

• 化驗: 97%
• 光學活性: [α]20/D +160°, c = 1 in methanol
• mp: 115.5-119.5 °C (lit.)
• SMILES 字串: CC[C@@]1(CCC(=O)NC1=O)c2ccc(N)cc2
• InChI: 1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)/t13-/m1/s1
• InChI 密鑰: ROBVIMPUHSLWNV-CYBMUJFWSA-N
• 基因資訊: human ... CYP17A1(1586) , CYP19A1(1588)

说明

應用

(R)-(+)-Aminoglutethimide can be used:

• As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
• To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
• To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves