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應用
2,4,5-Trifluorobenzaldehyde may be used in the synthesis of:
- bis(2,4,5-trifluorophenyl)methanone
- 8-phenyl-7-tosyl-1-(2,4,5-trifluorophenyl)octahydro-1H-pyrano[3,4-c] pyridine
- (E)-4-methoxy-N′-(2,4,5-trifluorobenzylidene)-benzohydrazide monohydrate
訊號詞
Warning
危險分類
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
138.2 °F - closed cup
閃點（°C）
59 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Aminol initiated Prins cyclization for the synthesis of octahydro-1H-pyrano [3, 4-c] pyridine and hexahydro-1H-furo [3, 4-c] pyrrole derivatives.
Tetrahedron Letters, 55(34), 4817-4821 (2014)
Zachary R Woydziak et al.
The Journal of organic chemistry, 77(1), 473-481 (2011-11-25)
Fluorination of fluorophores can substantially enhance their photostability and improve spectroscopic properties. To facilitate access to fluorinated fluorophores, bis(2,4,5-trifluorophenyl)methanone was synthesized by treatment of 2,4,5-trifluorobenzaldehyde with a Grignard reagent derived from 1-bromo-2,4,5-trifluorobenzene, followed by oxidation of the resulting benzyl alcohol.
Zachary R Woydziak et al.
Synthesis, 46(2), 158-164 (2014-06-11)
Fluorinated fluorophores are valuable tools for studies of biological systems. However, amine-reactive single-isomer derivatives of these compounds are often very expensive. To provide an inexpensive alternative, we report a practical synthesis of 4-carboxy-Pennsylvania Green methyl ester. Derivatives of this hydrophobic
(E)-4-Methoxy-N'-(2, 4, 5-trifluorobenzylidene) benzohydrazide monohydrate.
Maheswari R, et al.
IUCrJ, 1(5), x160846-x160846 (2016)
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