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Merck

490709

Sigma-Aldrich

丙酮酸钠-1-13C

99 atom % 13C

别名:

丙酮酸-1-13C 钠盐

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About This Item

线性分子式:
CH3CO13CO2Na
CAS号:
分子量:
111.04
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.12

同位素純度

99 atom % 13C

形狀

solid

技術

mass spectrometry (MS): suitable

mp

>300 °C (lit.)

質量偏移

M+1

儲存溫度

2-8°C

SMILES 字串

[Na+].CC(=O)[13C]([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i3+1;

InChI 密鑰

DAEPDZWVDSPTHF-FJUFCODESA-M

應用

Sodium pyruvate-1-13C results in sensitivity gains that allow disease tracking and interrogation of cellular metabolism by magnetic resonance. Intravenous administration of hyperpolarized [13C]pyruvate enables real-time detection of metabolism by magnetic resonance spectroscopic imaging (MRSI). It is used as a precursor in estimating many volatile organic compounds for use in studying terrestrial biosphere.

包裝

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Sens. 1B

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Kolby J Jardine et al.
Environmental science & technology, 44(7), 2454-2460 (2010-03-10)
Pyruvic acid, central to leaf carbon metabolism, is a precursor of many volatile organic compounds (VOCs) that impact air quality and climate. Although the pathways involved in the production of isoprenoids are well-known, those of several oxygenated VOCs remain uncertain.
Wissam Iali et al.
Angewandte Chemie (International ed. in English), 58(30), 10271-10275 (2019-05-23)
Hyperpolarisation methods that premagnetise agents such as pyruvate are currently receiving significant attention because they produce sensitivity gains that allow disease tracking and interrogation of cellular metabolism by magnetic resonance. Here, we communicate how signal amplification by reversible exchange (SABRE)
Jun Zhao et al.
Cell metabolism, 31(5), 937-955 (2020-04-24)
Cell proliferation and inflammation are two metabolically demanding biological processes. How these competing processes are selectively executed in the same cell remains unknown. Here, we report that the enzyme carbamoyl-phosphate synthetase, aspartyl transcarbamoylase, and dihydroorotase (CAD) deamidates the RelA subunit
Maria J Gonzalez-Rellan et al.
Nature communications, 12(1), 5068-5068 (2021-08-22)
p53 regulates several signaling pathways to maintain the metabolic homeostasis of cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes cellular metabolic stress, and we hypothesized that p53 could be linked to glucose maintenance. We

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Sigma-Aldrich.com presents an article concerning MRI/MRS and the use of isotopes in hyperpolarization.

Dynamic Nuclear Polarization (DNP) is a phenomenon by which high spin polarization, typically derived from a bath of free radical electrons, is transferred to a nuclear spin bath, enhancing the difference between the nuclear energy levels and thereby producing dramatically enhanced NMR signals for detection.

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