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Merck

476870

Sigma-Aldrich

α-氰基-4-羟基肉桂酸

99%

别名:

α-CCA, α-CHCA, α-氰基, 4-HCCA, ACCA

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About This Item

线性分子式:
HOC6H4CH=C(CN)CO2H
CAS号:
分子量:
189.17
Beilstein:
3271427
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

solid

mp

245-250 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

InChI 密鑰

AFVLVVWMAFSXCK-VMPITWQZSA-N

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一般說明

α-氰基-4-羟基肉桂酸是通过基质辅助激光解吸/电离质谱分析肽的常用基质。它抑制蘑菇酪氨酸酶的单酚酶活性和二酚酶活性。

應用

α-氰基-4-羟基肉桂酸(CHC)用于将CHC封装到NaY沸石中。使用几种成熟的体外血管新生试验,将其用作基质来研究紫杉醇衍生物的活性。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1B

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Inhibitory effects of α-cyano-4-hydroxycinnamic acid on the activity of mushroom tyrosinase.
Qiu L, et al.
Food Chemistry, 112(3), 609-613 (2009)
Encapsulation of α-cyano-4-hydroxycinnamic acid into a NaY zeolite.
Vilaca N, et al.
J. Mater. Sci., 46(23), 7511-7516 (2011)
Claudia Ryppa et al.
International journal of pharmaceutics, 368(1-2), 89-97 (2008-11-11)
The alpha(v)beta(3) integrin is overexpressed on proliferating endothelial cells such as those present in growing tumors as well as on tumor cells of various origins. Tumor-induced angiogenesis can be inhibited in vivo by antagonizing the alpha(v)beta(3) integrin with small peptides
Yusaku Hioki et al.
Journal of mass spectrometry : JMS, 48(11), 1217-1223 (2013-11-22)
We describe here an optimization study of the sample preparation conditions for sensitive detection of peptides by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Among many factors in the conditions, we varied the percent acetonitrile in the peptide solution, the percent
Robert Erne et al.
Analytical chemistry, 91(6), 4132-4139 (2019-03-01)
Contamination is a highly controversial issue in hair analysis. Therefore, hair testing protocols typically include wash steps to remove contamination. However, recent studies claim that washing could also lead to permanent incorporation of contaminants into hair, thus questioning the validity

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