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品質等級
化驗
95%
mp
209-214 °C (lit.)
官能基
amide
chloro
SMILES 字串
COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(N)(=O)=O
InChI
1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22)
InChI 密鑰
KVWWTCSJLGHLRM-UHFFFAOYSA-N
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一般說明
5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide is an organic building block. It has been reported as an intermediate in the synthesis of glyburide. Synthesis of 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide has been reported.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Journal of cardiovascular pharmacology, 63(4), 316-322 (2013-12-18)
The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitro but requires very high doses in vivo, associated with hypoglycemia. The aim
Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction.
International Heart Journal, 55(4), 380-380 (2014)
Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways
Journal of Cerebral Blood Flow and Metabolism (2014)
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