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化驗
95%
光學活性
[α]22/D +44°, neat
折射率
n20/D 1.481 (lit.)
bp
90 °C/18 mmHg (lit.)
密度
0.909 g/mL at 25 °C (lit.)
SMILES 字串
C[C@@H]1[C@@H](N)C[C@H]2C[C@@H]1C2(C)C
InChI
1S/C10H19N/c1-6-8-4-7(5-9(6)11)10(8,2)3/h6-9H,4-5,11H2,1-3H3/t6-,7+,8-,9-/m0/s1
InChI 密鑰
VPTSZLVPZCTAHZ-KZVJFYERSA-N
應用
(1S,2S,3S,5R)-(+)-isopinocampheylamine is a primary bicyclic amine with potent M2 ion channel inhibitor ability similar to that of amantadine, making it a promising candidate for developing anti-influenza agents.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
161.6 °F - closed cup
閃點(°C)
72 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Discovery of highly potent agents against influenza A virus.
European Journal of Medicinal Chemistry, 46(1), 52-57 (2011)
Identification of hits as matrix-2 protein inhibitors through the focused screening of a small primary amine library.
Journal of Medicinal Chemistry, 53(9), 3831-3834 (2010)
New strategy for high throughput screening of anti-influenza virus M2 ion channel inhibitors.
Current Pharmaceutical Design, 19(28), 5146-5155 (2013)
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