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Merck

38827

Sigma-Aldrich

4,4′-二甲氧基三苯甲基氯

≥97.0% (HPLC)

别名:

4,4′-二甲氧基氯化三苯甲烷, DMT, DMT-Cl, 氯-4,4′-二甲氧基三苯基甲烷

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About This Item

经验公式(希尔记法):
C21H19ClO2
CAS号:
分子量:
338.83
Beilstein:
2471942
EC號碼:
MDL號碼:
分類程式碼代碼:
12352101
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥97.0% (HPLC)

mp

123-125 °C

官能基

chloro
phenyl

SMILES 字串

COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3

InChI

1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3

InChI 密鑰

JBWYRBLDOOOJEU-UHFFFAOYSA-N

應用

4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
  • For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
  • For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.

其他說明

有用的保护基团试剂;移除

訊號詞

Danger

危險分類

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8B - Non-combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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其他客户在看

Slide 1 of 2

1 of 2

M.P. Reddy et al.
Tetrahedron Letters, 28, 23-23 (1987)
V. Amarnath et al.
Chemical Reviews, 77, 183-183 (1977)
Selective protection and deprotection procedures for thiol and hydroxyl groups
Huang Z and Benner SA
Synlett, 1993(01), 83-84 (1993)
A novel entry to 2′-O-aminopropyl modified nucleosides amenable for further modifications
Haas J and Engels JW
Tetrahedron Letters, 48(50), 8891-8894 (2007)
2′-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine
Seela F and Ming X
Organic & Biomolecular Chemistry, 6(8), 1450-1461 (2008)

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