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品質等級
化驗
≥97.0% (HPLC)
mp
123-125 °C
官能基
chloro
phenyl
SMILES 字串
COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
InChI
1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
InChI 密鑰
JBWYRBLDOOOJEU-UHFFFAOYSA-N
基因資訊
human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)
rat ... Htr1a(24473) , Htr2a(29595)
應用
4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
- For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
- For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.
其他說明
有用的保护基团试剂;移除
訊號詞
Danger
危險分類
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
8B - Non-combustible corrosive hazardous materials
水污染物質分類(WGK)
WGK 3
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Tetrahedron Letters, 28, 23-23 (1987)
Chemical Reviews, 77, 183-183 (1977)
Selective protection and deprotection procedures for thiol and hydroxyl groups
Synlett, 1993(01), 83-84 (1993)
A novel entry to 2′-O-aminopropyl modified nucleosides amenable for further modifications
Tetrahedron Letters, 48(50), 8891-8894 (2007)
2′-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine
Organic & Biomolecular Chemistry, 6(8), 1450-1461 (2008)
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