推荐产品
化驗
98%
mp
138-140 °C (lit.)
官能基
amide
SMILES 字串
Cc1cccc(c1)C(=O)NCC(O)=O
InChI
1S/C10H11NO3/c1-7-3-2-4-8(5-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)
InChI 密鑰
YKAKNMHEIJUKEX-UHFFFAOYSA-N
一般說明
3-Methylhippuric acid is also referred as m-methyl-hippuric acid. It is major product of xylene biotransformation in urine.
應用
3-Methylhippuric acid was employed as biological marker in studies on occupational exposure to xylene (solvent).
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
International archives of occupational and environmental health, 63(1), 33-37 (1991-01-01)
The industrial solvents, toluene and xylene, have physicochemical properties that can be hazardous to the workers exposed. Since hippuric acid and m-methyl-hippuric acid represent the products of toluene and xylene biotransformation in urine, they are used as biological markers in
British journal of industrial medicine, 45(2), 127-132 (1988-02-01)
In a series of experiments to investigate interactions between industrial solvents and common medications the interaction between m-xylene and aspirin was studied. As both these substances are metabolised and excreted as glycine conjugates there would possibly be competition for this
Determination of methylhippuric acid in human urine by high-performance liquid chromatography and by isotachophoresis.
Journal of chromatography, 343(2), 419-423 (1985-10-11)
Journal of chromatography, 573(2), 318-322 (1992-01-17)
A high-performance liquid chromatographic method is described for the simultaneous determination of six urinary metabolites of several aromatic chemicals: phenol (from benzene), hippuric acid (from toluene), 3-methylhippuric acid (from xylene), mandelic and phenylglyoxylic acid (from styrene) and 4-nitrophenol (from nitrobenzene).
Possible preferential metabolism of xylene isomers following occupational exposure to mixed xylenes.
International archives of occupational and environmental health, 72(2), 89-97 (1999-04-10)
Solvent exposures commonly involve mixtures of substances or mixtures of isomers of a single solvent. These may be metabolised through common pathways, resulting in the potential for metabolic interactions. These may then lead to accumulation of solvent or metabolic intermediates
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