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Merck

270873

Sigma-Aldrich

2-羟基喹啉

98%

别名:

2-喹啉醇, 喹诺酮

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About This Item

经验公式(希尔记法):
C9H7NO
CAS号:
分子量:
145.16
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

crystals

mp

198-199 °C (lit.)

溶解度

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

SMILES 字串

Oc1ccc2ccccc2n1

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

InChI 密鑰

LISFMEBWQUVKPJ-UHFFFAOYSA-N

一般說明

2-羟基喹啉是噬菌体对氧磷酶 1(PON1)的特异性抑制剂

應用

2-羟基喹啉用于获得具有向较长波长偏移的强波段的铂(IV)配合物的设计。Pt(IV)配合物是惰性稳定的前药,可被光激活,产生具有潜在抗癌活性的 Pt(II)物质

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Hui-Chung Tai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(34), 10630-10642 (2012-07-19)
Diazido Pt(IV) complexes are inert stable prodrugs that can be photoactivated to produce Pt(II) species with promising anticancer activity. Our studies of the photochemistry of Pt(IV) complexes, [Pt(X)(2) (Y)(2) (Z)(2) ](0/-1) (X=N-ligands (NH(3) , pyridine, etc.)/S(CH(3) )(2) /H(-) , Y=(pseudo)halogen
Kaitlyn M Ferguson et al.
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Cryptosporidium is a genus of single celled parasites capable of infecting a wide range of animals including humans. Cryptosporidium species are members of the phylum apicomplexa, which includes well-known genera such as Plasmodium and Toxoplasma. Cryptosporidium parasites cause a severe
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Microbial drug resistance (Larchmont, N.Y.), 23(5), 545-555 (2016-11-18)
Multidrug-resistant (MDR) Acinetobacter baumannii has increasingly emerged as an important nosocomial pathogen. The aim of this study was to determine the resistance profiles and genetic diversity in A. baumannii clinical isolates in a tertiary medical center in Malaysia. The minimum
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Journal of nanobiotechnology, 18(1), 51-51 (2020-03-20)
The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequently, preventing bacterial colonization of implanted prosthetic meshes is of major clinical relevance for patients undergoing

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