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Merck

188549

Sigma-Aldrich

2-巯基吡啶-N-氧化物

99%

别名:

2-硫代-1-氧化吡啶, 吡啶硫酮

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About This Item

经验公式(希尔记法):
C5H5NOS
CAS号:
分子量:
127.16
Beilstein:
109936
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

mp

69-72 °C (lit.)

SMILES 字串

[O-][n+]1ccccc1S

InChI

1S/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,8H

InChI 密鑰

FGVVTMRZYROCTH-UHFFFAOYSA-N

相关类别

一般說明

2-巯基吡啶 N 氧化物与氯化钯反应生成配合物 。它抑制从 克氏锥虫中提纯的 NADH 富马酸还原酶 。它是 O -酰基硫代异羟酸盐的前体 。它与金属连接形成具有生物活性的复合物

應用

2-巯基吡啶 N -氧化物被用于研究巯基吡啶- N -氧化物杀菌剂的光降解机理 。它被用于哺乳动物细胞内锌离子的比率荧光成像
O-酰基硫代异羟化物的前体。与金属连接形成具有生物活性的复合物。

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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The enzyme NADH-fumarate reductase is not found in mammalian cells but it is present in several parasitic protozoa including Trypanosoma cruzi, the parasite that causes Chagas' disease. This study shows that the drug 2-mercaptopyridine-N-oxide (MPNO) inhibits NADH-fumarate reductase purified from

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