推荐产品
产品名称
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉, ≥99%
化驗
≥99%
形狀
solid
反應適用性
reaction type: Coupling Reactions
mp
62-67 °C (lit.)
應用
peptide synthesis
官能基
ether
儲存溫度
2-8°C
SMILES 字串
CCOC1C=Cc2ccccc2N1C(=O)OCC
InChI
1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
InChI 密鑰
GKQLYSROISKDLL-UHFFFAOYSA-N
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一般說明
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉(EEDQ)是稳定试剂，可用于高产率制备酰胺和多肽。本品提供现成货品。室温下，可溶于含有机溶剂的水性介质，但不溶于水。 用作肽合成偶联剂。
應用
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉用作偶联剂：
- 用于壳聚糖及其两亲性衍生物的区域选择性季铵化。
- 用于制备酰胺型S-MA（扁桃酸）衍生物修饰的石英晶体微天平(QCM)传感器。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
H Gozlan et al.
Neuropharmacology, 33(3-4), 423-431 (1994-03-01)
The effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), an alkylating agent producing irreversible blockade of various membrane bound receptors in brain, were investigated on four different types of serotonin receptors, 5-HT1A, 5-HT1B, 5-HT2A and 5-HT3, in various brain regions in the rat. In
Kenichi Nagase et al.
Colloids and surfaces. B, Biointerfaces, 178, 253-262 (2019-03-16)
There is strong demand for cell separation methods that do not decrease cell activity or modify cell surfaces. Here, new temperature-modulated cell-separation columns not requiring cell-surface premodification are described. The columns were packed with temperature-responsive cationic polymer hydrogel-modified silica beads.
C Ribas et al.
British journal of pharmacology, 132(7), 1467-1476 (2001-03-27)
1. This study was designed to assess the molecular and cellular events involved in the up-regulation (and receptor supersensitivity) of brain alpha(2)-adrenoceptors as a result of chronic depletion of noradrenaline (and other monoamines) by reserpine. 2. Chronic reserpine (0.25 mg
G D Stanwood et al.
The Journal of pharmacology and experimental therapeutics, 295(3), 1232-1240 (2000-11-18)
Regulation of the expression of dopamine D2 and D3 receptors in the rat brain was examined using quantitative autoradiography after chronic (14 day) drug treatments designed to increase or decrease dopamine receptor stimulation. Reserpine treatment depleted endogenous dopamine by more
Didier Cussac et al.
Molecular pharmacology, 62(3), 578-589 (2002-08-16)
As determined by a guanosine 5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPgammaS) binding assay, which does not distinguish G protein subtypes, 5-hydroxytryptamine (5-HT) and 2(S)- 1-(6-chloro-5-fluoro-1H-indol-1-yl)-2-propanamine fumarate (Ro600175) behaved as full agonists at human 5-HT(2C) (h5-HT(2C)) receptors (VSV isoform) stably expressed in Chinese hamster ovary
实验方案
cAMP measurements are obtained using an ELISA assay (Harlow and Lane 1988). Commercial radio-immunoassays, or ELISA kits, to assay cAMP can be purchased from various manufacturers.
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