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品質等級
化驗
98%
形狀
solid
mp
56-58 °C (lit.)
溶解度
methanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow
官能基
disulfide
儲存溫度
2-8°C
SMILES 字串
S(Sc1ccccn1)c2ccccn2
InChI
1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H
InChI 密鑰
HAXFWIACAGNFHA-UHFFFAOYSA-N
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一般說明
醛糖醇™-2是一种核衣壳锌指靶标化合物,可以消除人免疫缺陷病毒1型 病毒的感染性。它是一种硫醇试剂。
應用
硫醇试剂。在高效液相色谱分离中,与 PPh3 一起作为缩合试剂,用于羧酸对映异构体的酰胺化作用。
醛糖醇™-2可用于合成腺苷-5′-磷酰咪唑内酯。它与PPh3一起使用,可作为HPLC分离羧酸对映体酰胺化反应的缩合剂。
法律資訊
Aldrithiol is a trademark of Sigma-Aldrich Co. LLC
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Tetrahedron Letters, 35, 1267-1267 (1994)
Analytical Sciences, 10, 17-17 (1994)
J L Rossio et al.
Journal of virology, 72(10), 7992-8001 (1998-09-12)
Whole inactivated viral particles have been successfully used as vaccines for some viruses, but procedures historically used for inactivation can denature virion proteins. Results have been inconsistent, with enhancement of disease rather than protection seen in some notable instances following
Journal of Chromatography A, 662, 87-87 (1994)
T L Dutka et al.
The Journal of physiology, 589(Pt 9), 2181-2196 (2010-12-01)
S-Nitrosoglutathione (GSNO) is generated in muscle and may S-glutathionylate and/or S-nitrosylate various proteins involved in excitation–contraction (EC) coupling, such as Na+-K+-ATPases, voltage-sensors (VSs) and Ca2+ release channels (ryanodine receptors,RyRs), possibly changing their properties. Using mechanically skinned fibres from rat extensor
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