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Merck

127221

Sigma-Aldrich

2-二吡啶基酮

99%

别名:

2,2′-二吡啶基甲酮, 双(2-吡啶基)甲酮

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About This Item

经验公式(希尔记法):
C11H8N2O
CAS号:
分子量:
184.19
Beilstein:
126598
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

solid

mp

52-55 °C (lit.)

官能基

ketone

SMILES 字串

O=C(c1ccccn1)c2ccccn2

InChI

1S/C11H8N2O/c14-11(9-5-1-3-7-12-9)10-6-2-4-8-13-10/h1-8H

InChI 密鑰

QPOWUYJWCJRLEE-UHFFFAOYSA-N

基因資訊

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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應用

di-2-吡啶基酮已被用于制备具有“星形”拓扑结构的异常 {Ni(II)(3)Ln(III)(μ-OR)(6)}(3+)络合物。其单阴离子形式已用于合成三角形 Ni(2)M(M = 镧系元素,Y)络合物

生化/生理作用

衍生自二-2-吡啶基酮的席夫碱配体在 SK-N-MC 神经上皮瘤(癌)细胞中表现出抗增殖活性

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Maram T Basha et al.
Dalton transactions (Cambridge, England : 2003), 41(21), 6536-6548 (2012-03-01)
The iron coordination and biological chemistry of a series of heterocyclic dithiocarbazate Schiff base ligands is reported with regard to their activity as Fe chelators for the treatment of Fe overload and also cancer. The ligands are analogous to tridentate
Constantinos G Efthymiou et al.
Inorganic chemistry, 49(21), 9737-9739 (2010-09-30)
Unusual {Ni(II)(3)Ln(III)(μ-OR)(6)}(3+) complexes with a "star" topology have been prepared with ligands derived from the metal-promoted reduction of di-2-pyridyl ketone under solvothermal conditions; the Dy(III) member shows weak single-molecule-magnet behavior.
Anastasia N Georgopoulou et al.
Dalton transactions (Cambridge, England : 2003), 46(38), 12835-12844 (2017-09-19)
The reaction of mixtures of Fe(O
Constantinos G Efthymiou et al.
Dalton transactions (Cambridge, England : 2003), 39(37), 8603-8605 (2010-08-04)
Using monoanionic forms of di-2-pyridyl ketone as the only primary ligand, triangular Ni(2)M (M = lanthanide, Y) complexes with interesting magnetic properties have been synthesized.
Gergely Szakacs et al.
FEBS letters, 594(23), 3965-3985 (2020-10-25)
ABC transporters fulfill diverse physiological functions in different cellular localizations ranging from the plasma membrane to intracellular membranous compartments. Several ABC transporters have been spotted in the endolysosomal system, which consists of endosomes, autophagosomes, lysosomes, and lysosome-related organelles. In this

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