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122505

2,3-二羟基吡啶

Name: 2,3-二羟基吡啶
Brand: ALDRICH

95%

别名:

2,3-吡啶二醇

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About This Item

经验公式（希尔记法）:

C₅H₅NO₂

CAS号:

16867-04-2

分子量:

111.10

Beilstein:

109848

EC號碼:

240-887-3

MDL號碼:

MFCD00006271

分類程式碼代碼:

12352100

PubChem物質ID:

24847492

NACRES:

NA.22

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T160121

2(1H)-PYRIDINONE

品質等級

100

化驗

95%

mp

245 °C (dec.) (lit.)

SMILES 字串

Oc1cccnc1O

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

InChI 密鑰

GGOZGYRTNQBSSA-UHFFFAOYSA-N

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應用

2,3-二羟基吡啶（DHP）用于通过偶氮偶合剂合成DHP负载的Amberlite XAD-2。通过使用连接基团 -NH-CH₂-CH₂-NH-SO₂-C₆H₄-N=N- 和 -SO₂-C₆H₄-N=N将DHP负载在纤维素上，可将DHP用于合成新型大分子螯合剂。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

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Sigma-Aldrich

C9750

β-胡萝卜素

2, 3-Dihydroxypyridine loaded amberlite XAD-2 (AXAD-2-DHP): preparation, sorption-desorption equilibria with metal ions, and applications in quantitative metal ion enrichment from water, milk and vitamin samples.

Venkatesh G, et al.

Microchimica Acta, 149(3-4), 213-221 (2005)

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Lei Wang et al.

European journal of medicinal chemistry, 156, 680-691 (2018-07-23)

Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl

Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.

Jayakanth Kankanala et al.

European journal of medicinal chemistry, 141, 149-161 (2017-10-17)

Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral

2,3-Dihydroxypyridine-loaded cellulose: a new macromolecular chelator for metal enrichment prior to their determination by atomic absorption spectrometry.

Vibha Gurnani et al.

Analytical and bioanalytical chemistry, 377(6), 1079-1086 (2003-08-09)

New macromolecular chelators have been synthesized, by loading 2,3-dihydroxypyridine (DHP) on cellulose via linkers -NH-CH(2)-CH(2)-NH-SO(2)-C(6)H(4)-N=N- and -SO(2)-C(6)H(4)-N=N-, and characterized by elemental analysis, TGA, IR, and CPMAS (13)C NMR spectra. The cellulose with DHP anchored by the shorter linker had better

Solvent effects on the electronic absorption spectra and acid strength of some substituted pyridinols.

Elham Y Hashem et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 58(2), 239-247 (2002-01-26)

The electronic absorption spectra of some substituted pyridinols in organic solvents of different polarities are studied. Also, the solvent effects on the intramolecular charge transfer bands are discussed using various solvent parameters. The acid-base equilibria of the compounds used are

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