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化驗
97%
mp
170-172 °C (dec.) (lit.)
溶解度
H2O: soluble 2.7 g/L at 20 °C
H2O: soluble 3.3 g/L at 30 °C
SMILES 字串
OC(O)=O.NNC(N)=N
InChI
1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4)
InChI 密鑰
OTXHZHQQWQTQMW-UHFFFAOYSA-N
應用
氨基胍重碳酸盐用于研究在 5 型腺病毒感染的大鼠胚胎细胞培养物中添加多胺的效果。
生化/生理作用
氨基胍重碳酸盐保护感染了腺病毒的细胞避免发生染色体损伤。氨基胍是一种二胺氧化酶(存在于胎牛血清中)的特异性和高效性抑制剂。
訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 2 - Skin Sens. 1
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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Methylglyoxal (MG) is a potent inducer of advanced glycation end products (AGEs). MG, long considered a highly cytotoxic molecule with potential anticancer value, is now being re-evaluated to a protumorigenic agent in some malignancies. Anaplastic thyroid cancer (ATC) is an
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Resveratrol (RSV) is well known for its many beneficial activities, but its unfavorable physicochemical properties impair its effectiveness after systemic and topical administration; thus, several strategies have been investigated to improve RSV efficacy. With this aim, in this work, we
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Methylglyoxal (MGO) is a reactive dicarbonyl produced as by-product of glycolysis, and its formation is heightened in hyperglycaemia. MGO plasma levels are two-fold to five-fold increased in diabetics and its accumulation promotes the progression of vascular complications. Impairment of endothelium-derived
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