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Merck

ITGAV

integrin, alpha V

别名:
CD51, MSK8, VNRA, VTNR
物种:
UniProtKB ID:
基因ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

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Small Molecule - Antagonist

Product Number
说明
物种
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
物种
human

Antibodies

Product Number
说明
物种反应性
应用
Anti-Integrin αVβ8 Antibody, clone EM13309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
抗-整合素α5(不含防腐剂)抗体,克隆SNAKA51, clone SNAKA51, from mouse, purified by using protein G,
物种反应性
human
应用
activity assay
immunocytochemistry

western blot
Anti-Integrin αVβ3 Antibody, clone EM22703 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry
Anti-Integrin αVβ5 Antibody, clone EM09902 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
抗-整合素α-V抗体,克隆272-17E6(不含叠氮化物), clone 272-17E6, from mouse,
物种反应性
human
应用
activity assay
flow cytometry

immunoprecipitation (IP)

Proteins

Product Number
说明
物种
人整合素αVβ3,辛基-β-D-吡喃葡萄糖苷处方, ,
物种
human

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Itgav,
物种
mouse
MISSION® esiRNA, targeting human ITGAV,
物种
human