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Merck

ITGA2B

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

别名:
BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3
物种:
UniProtKB ID:
基因ID:
  • Human(3674) Summary: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
  • Mouse(16399) integrin alpha 2b
  • Rat(685269) integrin, alpha 2B
  • Zebrafish(445380) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
  • dog(403789) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • domestic cat(101100930) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • cow(515011) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Horse(100009697) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • sheep(101115719) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • domestic guinea pig(100727374) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • naked mole-rat(101714332) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

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Small Molecule - Antagonist

货号
说明
物种
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
物种
human
阿司匹林, meets USP testing specifications,
物种
human
精氨酸-甘氨酸-天冬氨酸-丝氨酸, ≥95% (HPLC),
物种
mouse, human
乙酰水杨酸, analytical standard,
物种
human
乙酰水杨酸, ≥99.0%,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Integrin α2b (CD41) antibody, Mouse monoclonal, clone PM6/248, purified from hybridoma cell culture,
物种反应性
baboon, human
应用
flow cytometry
immunoprecipitation (IP)
Anti-CD41/ITGA2B antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Monoclonal Anti-CD41a antibody produced in mouse, clone HIP8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, nonhuman primates
应用
flow cytometry
Monoclonal Anti-CD41-FITC antibody produced in mouse, clone MEM-06, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
Anti-ITGA2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

Small Molecule - Inhibitor

货号
说明
物种
Tirofiban hydrochloride monohydrate, ≥98% (HPLC),
物种
human
替罗非班, ≥98.5% (HPLC),
物种
human
阿司匹林, meets USP testing specifications,
物种
human
乙酰水杨酸, analytical standard,
物种
human
乙酰水杨酸, ≥99.0%,
物种
human