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G6875

Sigma-Aldrich

α-D-Glucose 1-phosphate dipotassium salt hydrate

≥97% (HPLC)

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Empirical Formula (Hill Notation):
C6H11K2O9P · xH2O
CAS Number:
1233690-06-6
Molecular Weight:
336.32 (anhydrous basis)
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

synthetic

Quality Level

200

Assay

≥97% (HPLC)

form

powder

impurities

glucose, essentially free

color

white

solubility

water: slightly soluble 50 g/L

storage temp.

−20°C

SMILES string

[K+].[K+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2K.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

VOQGDSVKCMGEFO-FBNUBEQJSA-L

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General description

α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.

Linkage

Formerly listed as Grade I.

Preparation Note

Prepared by a modification of the procedure of McCready, R.M., et al., J. Am. Chem. Soc., 66, 560 (1944).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bijay Singh et al.
Protein engineering, design & selection : PEDS, 25(4), 179-187 (2012-02-16)
Two similar genes, dnmL and rmbA in Streptomyces peucetius, which encode for glucose-1-phosphate (G-1-P) thymidylyltransferases were expressed in Escherichia coli under similar conditions. While RmbA was expressed in soluble form, DnmL was found as insoluble aggregates in inclusion bodies. The
Kyra-Melinda Alexacou et al.
Bioorganic & medicinal chemistry, 18(22), 7911-7922 (2010-10-16)
Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(β-d-glucopyranosyl)thiosemicarbazones have been synthesized and evaluated as inhibitors of rabbit
Stanley A Blumenthal
Perspectives in biology and medicine, 55(2), 236-249 (2012-05-31)
In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in
Jef Van der Borght et al.
Biotechnology journal, 5(9), 986-993 (2010-08-28)
β-D-Glucose-1-phosphate (βGlc1P) is an efficient glucosyl donor for both enzymatic and chemical glycosylation reactions but is currently very costly and not available in large amounts. This article provides an efficient production method of βGlc1P from trehalose and phosphate using the
Cátia Nunes et al.
Plant physiology and biochemistry : PPB, 63, 89-98 (2012-12-22)
SnRK1 of the SNF1/AMPK group of protein kinases is an important regulatory protein kinase in plants. SnRK1 was recently shown as a target of the sugar signal, trehalose 6-phosphate (T6P). Glucose 6-phosphate (G6P) can also inhibit SnRK1 and given the
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Protocols

Enzymatic Assay of Phosphoglucomutase (EC 5.4.2.2)

This procedure may be used for all Phosphoglucomutase products except for Phosphoglucomutase, Catalog Number P4109.

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