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Key Documents

G6750

Sigma-Aldrich

α-D-Glucose 1-phosphate dipotassium salt hydrate

≥99% (HPLC), BioXtra

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Empirical Formula (Hill Notation):
C6H11K2O9P · xH2O
CAS Number:
Molecular Weight:
336.32 (anhydrous basis)
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

product line

BioXtra

Assay

≥99% (HPLC)

form

powder

impurities

glucose and starch, essentially free

color

white to off-white

solubility

water: 50 mg/mL, clear, colorless

cation traces

K: 20.4-26.1% (ICP)

storage temp.

−20°C

SMILES string

[K+].[K+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2K.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

VOQGDSVKCMGEFO-FBNUBEQJSA-L

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General description

α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.

Linkage

Formerly listed as Grade V.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nicole M Koropatkin et al.
The Journal of biological chemistry, 279(42), 44023-44029 (2004-08-05)
Dideoxysugars, which display biological activities ranging from mediating cell-cell interactions to serving as components in some antibiotics, are synthesized in various organisms via complex biochemical pathways that begin with the attachment of alpha-D-glucose 1-phosphate to either CTP or dTTP. Here
Bijay Singh et al.
Protein engineering, design & selection : PEDS, 25(4), 179-187 (2012-02-16)
Two similar genes, dnmL and rmbA in Streptomyces peucetius, which encode for glucose-1-phosphate (G-1-P) thymidylyltransferases were expressed in Escherichia coli under similar conditions. While RmbA was expressed in soluble form, DnmL was found as insoluble aggregates in inclusion bodies. The
Stanley A Blumenthal
Perspectives in biology and medicine, 55(2), 236-249 (2012-05-31)
In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in
Ting Yang et al.
The Biochemical journal, 429(3), 533-543 (2010-05-21)
The diverse types of glycoconjugates synthesized by trypanosomatid parasites are unique compared with the host cells. These glycans are required for the parasite survival, invasion or evasion of the host immune system. Synthesis of those glycoconjugates requires a constant supply
Cátia Nunes et al.
Plant physiology and biochemistry : PPB, 63, 89-98 (2012-12-22)
SnRK1 of the SNF1/AMPK group of protein kinases is an important regulatory protein kinase in plants. SnRK1 was recently shown as a target of the sugar signal, trehalose 6-phosphate (T6P). Glucose 6-phosphate (G6P) can also inhibit SnRK1 and given the

Articles

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.

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