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Merck

Properties of gelatin-based films incorporated with chitosan-coated microparticles charged with rutin.

International journal of biological macromolecules (2017-04-04)
Ilyes Dammak, Ana Mônica Quinta Barbosa Bittante, Rodrigo Vinicius Lourenço, Paulo José do Amaral Sobral
ABSTRAKT

The aim of this study was development an active film based on gelatin incorporated with antioxidant, rutin carried into microparticles. The complexation between oppositely charged lecithin and chitosan was applied to prepare the chitosan-coated microparticles. The generated microparticles had an average size of 520±4nm and a span of 0.3 were formulated by a rotor-stator homogenize at the homogenization speed 10,000rpm. Composite films were prepared by incorporating chitosan-coated microparticles, at various concentrations (0.05, 0.1, 0.5, or 1% (based on the weight of the gelatin powder)) in the gelatin-based films. For the prepared films, the results showed that obtained physicochemical, water vapor barrier, and mechanical were compared with native gelatin film with a slight decrease for chitosan concentration higher than 0.5%. The microstructure studies done by scanning electron microscopes, revealed different micropores embedded with oil resulting from the incorporation of the microparticles into the gelatin matrix. Moreover, the calorimetric results were comparable to those of gelatin control film with T

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Sigma-Aldrich
Rutin hydrate, ≥94% (HPLC), powder