Przejdź do zawartości
Merck
  • Protective effect of topically applied conjugated hexadienes against ultraviolet radiation-induced chronic skin damage in the hairless mouse.

Protective effect of topically applied conjugated hexadienes against ultraviolet radiation-induced chronic skin damage in the hairless mouse.

Photodermatology, photoimmunology & photomedicine (1990-04-01)
D L Bissett, S Majeti, J J Fu, J F McBride, W E Wyder
ABSTRAKT

Albino hairless mice (SkH:HR-1) exposed chronically to suberythemal doses of ultraviolet B (UVB) radiation display visible skin wrinkling and tumors. Topical treatment of mice with solutions of conjugated dienes (2,4-hexadien-1-ol and derivatives of it) prior to each UVB radiation exposure reduces significantly the severity of these visible alterations. Chronic suberythemal doses of ultraviolet A radiation induce skin sagging, a distinctly different visible skin alteration. The severity of skin sagging is not reduced by topical application of the conjugated dienes tested here.

MATERIAŁY
Numer produktu
Marka
Opis produktu

Sigma-Aldrich
trans,trans-2,4-Hexadien-1-ol, 97%