Przejdź do zawartości
Merck

Ag(I)-catalyzed aminofluorination of alkynes: efficient synthesis of 4-fluoroisoquinolines and 4-fluoropyrrolo[α]isoquinolines.

Organic letters (2012-10-24)
Tao Xu, Guosheng Liu
ABSTRAKT

A silver-catalyzed intramolecular oxidative aminofluorination of alkynes has been developed by using NFSI as a fluorinating reagent. This reaction represents an efficient method for the synthesis of various 4-fluoroisoquinolines and 4-fluoropyrrolo[α]isoquinolines.

MATERIAŁY
Numer produktu
Marka
Opis produktu

Sigma-Aldrich
Silver nitrate, BioReagent, suitable for plant cell culture, >99% (titration)
Sigma-Aldrich
Silver nitrate, BioXtra, >99% (titration)
Sigma-Aldrich
Silver nitrate, tested according to Ph. Eur.
Sigma-Aldrich
Silver nitrate, ReagentPlus®, ≥99.0% (titration)
Sigma-Aldrich
Silver nitrate, ACS reagent, ≥99.0%
Sigma-Aldrich
Silver nitrate, 99.9999% trace metals basis
Sigma-Aldrich
Silver nitrate on silica gel, extent of labeling: ~10 wt. % loading, +230 mesh
Sigma-Aldrich
Silver nitrate solution, 2.5 % (w/v) AgNO3 in H2O