- Mosaic hydrogels: one-step formation of multiscale soft materials.
Mosaic hydrogels: one-step formation of multiscale soft materials.
Advanced materials (Deerfield Beach, Fla.) (2012-06-21)
Lian Leng, Arianna McAllister, Boyang Zhang, Milica Radisic, Axel Günther
PMID22714644
ABSTRAKT
The one-step, continuous formation of mosaic hydrogel sheets is presented. A microfluidic device allows controllable incorporation of secondary biopolymers within a flowing biopolymer sheet followed by a cross-linking step that retains the microscale composition. Information is encoded; mosaic stiffness and diffusivity patterns are created; tessellations are populated with biomolecules, microparticles and viable primary cells; and 3D soft material assemblies are demonstrated.
MATERIAŁY